Dorthe Andersen became a doctor from Aarhus University and later specialized in gynaecology and obstetrics from Skejby University Hospital. As part of her training as a specialist in infertility, she worked at the Herning Central Hospital, Holstebro Hospital and most recently at Skejby University Hospital.

 

 

  Malene Kloster specialized in Gynaecology and Obstetrics from Odense University Hospital in 2013 and has worked at the Fertility Clinic, Odense University Hospital for two years before she joined IVF-SYD in September 2015.

 

 

 

Steen B. Laursen is a trained cell scientist from Odense University in 1989 and was awarded PhD in medicine from Aarhus University in 1998. He has 15 years' experience in infertility treatment at Odense University Hospital as well as in private practice.

He has also been engaged in stem cell research at Odense University Hospital and Copenhagen University Hospital.

     

 

Nurses

 

Heidi Andersen  
   
 
 Tina Jensen  
   
 
Lone Flensted  

 

Laboratory Technicians (B.Sci.)

 
Lone Henriksen  
   
Heidi Pasfall  
   
 
Lene Hegerlund  
   
 
Peter Givskov  

 

Secretary

 
Heidi Reis  

 

Service Assistant

 

Marianne Johannessen  
   

 

 
 Lotte Degn  

In connection with the transfer of embryos, we will inform you of how many of your eggs that qualify for freezing. In order to freeze fertilized eggs it is necessary that the eggs are of good quality, as they will otherwise not be able to withstand the biologically tough process associated with freezing and subsequent thawing. This means that although a large number of eggs have been retrieved, not all of them are suitable for freezing.

At our clinic, the laboratory applies a special freezing method – vitrification which we started in 2006 as the first clinic in Denmark. The method has slowly gained ground in the rest of Denmark, partly due to our good results and the international experience. Vitrification involves “flash-freezing” of the eggs whereby they suffer minimum freeze damage and consequently face better survival after thawing. Even with perfect eggs, only approximately 80% of the eggs survive the thawing process.

 Registering for freeze treatment – if you have a regular menstrual cycle

 On the first day of your period, please call us at +45  76 24 50 20 from 9.15-12.00 or from 12.30-2.30 p.m. and sign up for “freeze” treatment as well as make an appointment for a scan on Day 10-12 of your cycle (depending on the duration of your cycle). If your period arrives on a Friday after 2.30 p.m. or during the weekend, you can call us on the following Monday or immediately thereafter during telephone hours.

Typically, the time line of freeze treatment in a woman with a 28-day cycle is as follows:

Scan on Day 12, Ovitrelle injection on Dag 14, thawing of eggs on Day 17, and finally embryo transfer on Day 18 of the cycle. Each process is described in detail below.

Scan on Day 10-12 of menstrual cycle

On this day, the lining of the uterus is assessed and the dominant follicle in the ovary is measured. When it reaches a sufficient size (18mm) – which normally is a few days later – you must take the Ovitrell ovulation injection as instructed in order for ovulation to start.

Three days later, a suitable number of eggs are thawed, but not until the next day can we see if the eggs have survived the thawing process and have started to divide. If the eggs have not survived the thawing process, we will contact you in the morning and cancel embryo transfer.

Embryo transfer with thawed eggs

If the eggs have survived, you can come to the clinic as agreed for the embryo transfer. Remember that you must have a filled bladder! On the same day as the embryo transfer, you must inject half an Ovitrelle solution, which enhances progesterone production in the ovaries, whereby the uterus becomes more susceptible to the transferred embryos. Keep the syringe in the refrigerator until you have to inject the second half of the solution 4 days after embryo transfer. The time of day when the two solutions are injected is of no importance.

If the pregnancy test is positive, a pregnancy scan will be scheduled 3 weeks later.


Registering for frozen embryo transfer– if you have an irregular menstrual cycle or none at all

As mentioned above, you should call us on Day 1 of your menstrual period and register for freeze treatment.

On Day 2 of your menstrual period, you will start to take Femanest, 2 mg, 1 tablet x 3 daily, so do not forget to ask the secretary to fax a prescription to the nearest pharmacy if you do not already have the prescription or the pills at home.

The reason why Femanest, a female hormone, is administered is to thicken the lining of the uterus, thus making it more susceptible to the embryos.

You should make an appointment for a scan approximately 12 days after in order for us to assess the thickness of the uterus. If we consider it of a suitable measure, ie more than 7 mm thick, you must start with Crinone x 2 daily and continue with Femanest, 1 tablet x 3 daily.

Three days after, a suitable amount of eggs will be thawed, but not until the next day will we be able to see if the eggs have survived the thawing process and have started to divide. If the eggs have not survived, we will contact you in the morning and cancel embryo transfer.

If the eggs have survived, you should come to the clinic as agreed for embryo transfer. Remember to have a filled bladder!

After embryo transfer, you must continue with Femanest as well as Crinone until the pregnancy test 14 days later. If the test is positive, you should continue taking Femanest and Crinone until gestation week 7. The hormones will not affect the foetus.

A pregnancy scan will be performed 3 weeks after a positive test.

If the test is negative, treatment with Femanest and Crinone is terminated, and you will have to wait for your menstrual period which will appear in a few days.

What is the chance of pregnancy in the case of frozen embryos?

The pregnancy rate is approximately 25-33% for a positive pregnancy test after the transfer of two, maximum three, frozen embryos.

When can I start treatment again when the test after frozen embryo transfer turned out negative?

You can start again immediately and need not observe any interruption period.

Can we donate some of our eggs to other infertile couples when we are receiving treatment ourselves?

You may donate some of your unfertilized eggs, but our overall opinion is that you should think about yourselves.

Some women are offered IVF/ICSI due to their husband’s reduced sperm quality. These women do not themselves suffer from reduced fertility, and they produce many fine eggs which they would like to pass on to others. In principle, more than 8 mature eggs should be retrieved you think about egg donation. Therefore, the final decision concerning egg donation is made at the actual retrieval of eggs.

You can only donate eggs if you are under the age of 36, are healthy and suffer from no hereditary diseases in the family. In addition to the HIV, Hepatitis B and C tests, to which you have already been subjected, you will have a blood sample drawn at the clinic. This sample will be tested for syphilis and gonorrhea. You will be informed verbally about the consequences of your egg donation, and you must therefore provide a written consent.

Donation is anonymous, and you will not be informed of the name of the recipient nor of the child’s identity. For further information about this, please see the section on egg donation.

 You can download this patient information by clicking her.

 

 

Absence of sperm in the semen sample

If there are no sperm cells in the semen sample (azoospermia) made at either the local hospital or here at the clinic, this could indicate no production of sperm in the testicles or absence of sperm in the ejaculate.

Lack of production of sperm in the testicle can be a result of a congenital defect in the testicular tissue, whereas lack of sperm in the ejaculate could be explained by blockage of the sperm carrying ducts, for instance caused by a Chlamydia infection.

Whether or not there are live sperm in the testicular tissues is determined by taking a small tissue sample from the testicle (testis biopsy). If this biopsy reveals that in fact there are sperm, it is possible to perform the same procedure again when subjecting the female to IVF treatment, where by using micro-insemination (ICSI) the eggs are fertilized with the male’s sperm (see description in next section under TESA)

If there are no sperm in the testis biopsy, donor insemination can be performed.

Testis  biopsy
The procedure, which is completely painless, is performed here at the clinic and lasts approximately half an hour. The couple will be given the result immediately after the procedure. We place a local anaesthesia in the groin and the scrotum, and initiate antiseptic procedures while the local anaesthesia starts to work. You may be given analgesics (morphine) intravenously (in a vein) via a needle inserted in your hand. After approximately 5 minutes, the sample is aspirated from the testicle using a thin needle. Most men only experience slight discomfort in connection with the procedure. The retrieved material is analysed at the clinic laboratory for the presence of sperm.

After the procedure
You might feel a slight pain in the scrotum and the groin for a few days after the procedure, and we recommend that you take it easy during this period. You can go to work, if only you refrain from strenuous physical work. Painkillers such as Panodil can be taken as needed, but no more than 2 tablets (500 mg) x 4 daily.

If you experience strong pain, swelling, redness or fever, please contact Fertilitetsklink IVF-SYD or your own GP/emergency service doctor. However, this happens very rarely.

TESA
Men who have previously been sterilized or men, in which the above testis biopsy has shown sperm in the testicle, may have their sperm removed from the testicle by a procedure known as Testicular Sperm Aspiration (TESA) in connection with IV treatment. These sperm can be isolated and used for the fertilization of the female’s eggs after egg retrieval.

After sterilisation, it will normally be possible to find sperm, even though the sterilisation procedure was carried out many years ago.

Retrieval of sperm from testicles in connection with IVF treatment.
TESA  is performed on the same day and preferably the day before the female’s eggs are retrieved. TESA is performed in the exact same manner as under the testis  biopsy section above. Only a few sperm are retrieved in connection with a TESA as it is only necessary to retrieve the same number of sperm as number of eggs. Due to the small quantity of sperm, we always fertilize the female’s eggs via micro-insemination (Intra Cytoplasmatic Sperm Injection). During the ICSI procedure, the single sperm is injected under a microscope into the egg by means of a tiny glass needle.

In very few instances, we see that there are no live sperm in the retrieved material, even though previous samples have proven otherwise. Therefore, prior to sperm retrieval you should decide what should happen if this situation arises. Should the retrieved eggs be fertilized with donor sperm, should they be destroyed, or should they be frozen as non-fertilized eggs?.

If you wish to download this patient information, please click her.

Absence of sperm in the semen sample

If there are no sperm cells in the semen sample (azoospermia) made at either the local hospital or here at the clinic, this could indicate no production of sperm in the testicles or absence of sperm in the ejaculate.

Lack of production of sperm in the testicle can be a result of a congenital defect in the testicular tissue, whereas lack of sperm in the ejaculate could be explained by blockage of the sperm carrying ducts, for instance caused by a Chlamydia infection.

Whether or not there are live sperm in the testicular tissues is determined by taking a small tissue sample from the testicle (testis biopsy). If this biopsy reveals that in fact there are sperm, it is possible to perform the same procedure again when subjecting the female to IVF treatment, where by using micro-insemination (ICSI) the eggs are fertilized with the male’s sperm (see description in next section under TESA)

If there are no sperm in the testis biopsy, donor insemination can be performed.

Testis  biopsy
The procedure, which is completely painless, is performed here at the clinic and lasts approximately half an hour. The couple will be given the result immediately after the procedure. We place a local anaesthesia in the groin and the scrotum, and initiate antiseptic procedures while the local anaesthesia starts to work. You may be given analgesics (morphine) intravenously (in a vein) via a needle inserted in your hand. After approximately 5 minutes, the sample is aspirated from the testicle using a thin needle. Most men only experience slight discomfort in connection with the procedure. The retrieved material is analysed at the clinic laboratory for the presence of sperm.

After the procedure
You might feel a slight pain in the scrotum and the groin for a few days after the procedure, and we recommend that you take it easy during this period. You can go to work, if only you refrain from strenuous physical work. Painkillers such as Panodil can be taken as needed, but no more than 2 tablets (500 mg) x 4 daily.

If you experience strong pain, swelling, redness or fever, please contact Fertilitetsklink IVF-SYD or your own GP/emergency service doctor. However, this happens very rarely.

TESA
Men who have previously been sterilized or men, in which the above testis biopsy has shown sperm in the testicle, may have their sperm removed from the testicle by a procedure known as Testicular Sperm Aspiration (TESA) in connection with IV treatment. These sperm can be isolated and used for the fertilization of the female’s eggs after egg retrieval.

After sterilisation, it will normally be possible to find sperm, even though the sterilisation procedure was carried out many years ago.

Retrieval of sperm from testicles in connection with IVF treatment.
TESA  is performed on the same day and preferably the day before the female’s eggs are retrieved. TESA is performed in the exact same manner as under the testis  biopsy section above. Only a few sperm are retrieved in connection with a TESA as it is only necessary to retrieve the same number of sperm as number of eggs. Due to the small quantity of sperm, we always fertilize the female’s eggs via micro-insemination (Intra Cytoplasmatic Sperm Injection). During the ICSI procedure, the single sperm is injected under a microscope into the egg by means of a tiny glass needle.

In very few instances, we see that there are no live sperm in the retrieved material, even though previous samples have proven otherwise. Therefore, prior to sperm retrieval you should decide what should happen if this situation arises. Should the retrieved eggs be fertilized with donor sperm, should they be destroyed, or should they be frozen as non-fertilized eggs?.

Unfortunately, there is no subsidy on medicine for foreign patients receiving treatment in Denmark.

You can see our pricelist for treatment (excluding medicine) by clicking here.